Anke Reinders, Ph.D. Research Associate

CV

Research Interests

My research currently focuses on studying the activity of sucrose and other metabolite transporters by heterologous expression in both yeast and Xenopus oocytes. Recently I have worked on sucrose transporters from Arabidopsis, barley and sugarcane, as well as a broad-specificity monosaccharide and sugar alcohol transporter from Arabidopsis (PLT5). I am also interested in mechanisms by which membrane transporters are regulated at the protein level.

Publications

Sivitz A.B., Reinders A., Ward J.M. (2008) Arabidopsis sucrose transporter AtSUC1 is important for pollen germination and sucrose-induced anthocyanin accumulation. Plant Physiol. in press

Sivitz, A.B., Reinders, A., Johnson, M.E., Krentz, A.D., Grof C.P.L., Perroux, J.M., Ward, J.M. (2007) Arabidopsis sucrose transporter AtSUC9. High-affinity transport activity, intragenic control of expression, and early flowering mutant phenotype. Plant Physiol 143: 188–198

Reinders, A., Sivitz, A.B., Hsi, A., Grof, C.P.L., Perroux, J.M., Ward, J.M. (2006) Sugarcane ShSUT1: analysis of sucrose transport activity and inhibition by sucralose. Plant Cell Environ 29(10): 1871-80

Sivitz, A.B., Reinders, A., Ward, J.M. (2005) Analysis of the Transport Activity of Barley Sucrose Transporter HvSUT1. Plant Cell Physiol. 46(10): 1666-73

Reinders, A., Panshyshyn, J.A., Ward, J.M. (2005) Analysis of transport activity of Arabidopsis sugar alcohol permease homolog AtPLT5. J Biol Chem 280(2):1594-602

Chandran, D., Reinders, A., Ward, J.M. (2003) Substrate specificity of the Arabidopsis thaliana sucrose transporter AtSUC2. J Biol Chem 278(45): 44320-5

Schulze, W. X., Reinders, A., Ward, J., Lalonde, S. and Frommer, W.B. (2003) Interactions between co-expressed Arabidopsis sucrose transporters in the split-ubiquitin system. BMC Biochem. 4:3

Reinders, A., Schulze, W., Kühn, C., Barker, L., Schulz, A., Ward, J.M. and Frommer, W.B. (2002) Protein-protein interactions between sucrose transporters of different affinities colocalized in the same enucleate sieve element. Plant Cell 14: 1567-1577.

Reinders, A., Schulze, W., Thaminy, S., Stagljar, I., Frommer, W.B. and Ward, J.M. (2002) Intra- and intermolecular interactions in sucrose transporters at the plasma membrane detected by the split-ubiquitin system and functional assays. Structure 10(6): 763-772.

Reinders, A. and Ward, J. M. (2001) Functional characterization of the a-glucoside transporter Sut1p from Schizosaccharomyces pombe, the first fungal homologue of plant sucrose transporters. Mol Microbiol 39: 445-454.

Reinders, A., Romano, I., Wiemken, A., De Virgilio, C. (1999) The thermophilic yeast Hansenula polymorpha does not require trehalose synthesis for growth at high temperatures but does for normal acquisition of thermotolerance. J Bacteriol 181: 4665-4668.

Bell, W., Sun, W., Hohmann, S., Wera, S., Reinders, A., De Virgilio, C., Wiemken, A. and Thevelein, J.M. (1998) Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex. J Biol Chem 273:33311-33319.

Reinders, A., Bürckert, N., Boller, T., Wiemken, A. and De Virgilio, C. (1998) Saccharomyces cerevisiae cAMP-dependent protein kinase controls entry into stationary phase through the Rim15 protein kinase. Genes Dev 12: 2943-2955.

Ribeiro, M., Reinders, A., Boller, T., Wiemken, A. and De Virgilio, C. (1997) Trehalose synthesis is important for the acquisition of thermotolerance in Schizosaccharomyces pombe. Mol Microbiol 25: 571-581.

Reinders, A., Bürckert, N., Hohmann, S., Thevelein, J. M., Boller, T., Wiemken, A. and De Virgilio, C. (1997) Structural analysis of the subunits of the trehalose-6-phosphate synthase/phosphatase complex in Saccharomyces cerevisiae and their function during heat shock. Mol Microbiol 24: 687-695.

Ward, J. M., Reinders, A., Hsu, H.-T. and Sze, H. (1992) Dissociation and reassembly of the vacuolar H+-ATPase-complex from oat roots. Plant Physiol 99:161-169